FAMILIAL OCCURRENCE OF BERRY ANEURYSM
FAMILIAL OCCURRENCE OF BERRY ANEURYSM
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DOI：
10.1136/jnnp.31.4.399
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发表时间：
1968-01-01
影响因子：
11
通讯作者：
BEUMONT, PJV
中科院分区：
文献类型：
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作者：
BEUMONT, PJV
1954 年，钱伯斯、哈珀和辛普森写道，“据作者所知，脑内动脉瘤的发生可能存在家族因素，但这种可能性尚未得到证实”。然而，奥布莱恩在 1942 年报道了一名患有中脑动脉瘤的患者，他的双胞胎兄弟八年前在强烈提示蛛网膜下腔出血的情况下死亡。 Jokl 和 Wolffe (1954) 描述了一对类似的同卵双胞胎。自 1954 年以来，已经发表了几篇关于不止一名家庭成员患有颅内动脉瘤的报告。本文的目的是介绍一个家庭，其中三名成员患有先天性颅内血管病变。将提供三姐妹的病史和相关放射学检查结果。其中两例颅内动脉瘤破裂几乎发生在生命的同一时间。第三个病例相当年轻，是在精神疾病过程中偶然发现的，伴有动脉瘤的血管瘤。将参考英语文献中引用的那些发生在一个以上家庭成员中的颅内动脉瘤的实例。
In 1954 Chambers, Harper, and Simpson wrote'that there may be a familial factor in the occurrence of intracerebral aneurysm is a possibility that has not been advanced, to the knowledge of the authors'. However, O'Brien in 1942 had reported a case of middle cerebral aneurysm in a man whose twin brother had died eight years previously under conditions strongly suggestive of subarachnoid haemorrhage. A similar pair of identical twins was described by Jokl and Wolffe (1954). Since1954 several reports of intracranial aneurysm inmore than one member of a family have been published. The purpose of this paper is to present a family in which three members have had congenital intracranial vascular lesions. The case histories and re-levant radiological findings of three sisters will be given. In two of these cases rupture of an intracranial aneurysm occurred at approximately the same time in life. In the third case, considerably younger, an angioma with an associated aneurysm was discovered incidentally during the course of a psychiatric illness. Reference will be made to those instances of intracranial aneurysm occurring in more than one member of a family that have been cited in the English language literature.