Circulating Osteogenic Cells: Implications for Injury, Repair, and Regeneration
Circulating Osteogenic Cells: Implications for Injury, Repair, and Regeneration
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DOI：
10.1002/jbmr.370
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发表时间：
2011-08-01
影响因子：
6.2
通讯作者：
Kassem, Moustapha
中科院分区：
文献类型：
--
作者：
Pignolo, Robert J.;Kassem, Moustapha
这篇综述的目的是提供一个关键的阅读最近的文献有关的循环，液相成骨细胞的存在和他们可能的贡献骨形成。我们将这组细胞统称为循环成骨前体（COP）细胞。我们目前的证据，他们的存在，用于他们的分离和鉴定，可能的生理和病理生理作用，细胞起源，以及可能的机制，他们迁移到靶组织的方法。(C)2011年美国骨与矿物质研究学会。
The aim of this review is to provide a critical reading of recent literature pertaining to the presence of circulating, fluid-phase osteoblastic cells and their possible contribution to bone formation. We have termed this group of cells collectively as circulating osteogenic precursor (COP) cells. We present evidence for their existence, methods used for their isolation and identification, possible physiological and pathophysiological roles, cellular origins, and possible mechanisms for their migration to target tissues. (C) 2011 American Society for Bone and Mineral Research.