CARDIOPULMONARY-RESUSCITATION IN VERY-LOW-BIRTH-WEIGHT INFANTS
CARDIOPULMONARY-RESUSCITATION IN VERY-LOW-BIRTH-WEIGHT INFANTS
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DOI：
10.1055/s-2007-994686
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发表时间：
1992-03-01
影响因子：
2
通讯作者：
GIACOIA, GP
中科院分区：
文献类型：
--
作者：
SOOD, S;GIACOIA, GP
在 2 年内入住我们新生儿重症监护室的 191 名出生体重低于 1500 克的患者中，41 人接受了心肺复苏 (CPR)。 41 名极低出生体重 (VLBW) 患者中，有 11 名 (27%) 存活并出院。出生 72 小时后接受心肺复苏的婴儿无一幸存。此外，所有在产房和新生儿重症监护室 (NICU) 接受心肺复苏的婴儿均死亡。区分幸存者和非幸存者的最重要因素是后者在 CPR 前 20 小时表现出升压药无反应性低血压。这项研究证实了极低出生体重婴儿在心肺复苏后的存活率非常低。我们的结论是，对升压药无反应性低血压或既往产房复苏的患者进行心肺复苏应被视为抢救或实验性治疗，并且应给予父母不复苏的选择。未来的研究工作应致力于更好地理解和治疗心脏骤停前的心血管功能障碍。
Of 191 patients with birthweight less than 1500 gm admitted to our neonatal intensive care unit in a 2-year period, 41 underwent cardiopulmonary resuscitation (CPR). Eleven of 41 very low birthweight (VLBW) (27%) survived to be discharged. None of the infants who received CPR after 72 hours of life survived. Also, all infants who underwent CPR, both in the delivery room and neonatal intensive care unit (NICU), died. The most significant factor distinguishing survivors from nonsurvivors was the demonstration of vasopressor unresponsive hypotension 20 hours prior to CPR in the latter group. This study confirmed the very poor survival rate after CPR in VLBW infants. We conclude that performance of CPR in patients with vasopressor unresponsive hypotension or previous delivery room resuscitation should be considered a rescue or experimental treatment and parents should be given the option of no resuscitation. Future research efforts should be directed to better the understanding and treatment of cardiovascular dysfunction prior to cardiac arrest.