ADVERSE REACTIONS TO PRESCRIBED DRUGS IN THE ELDERLY - A MULTICENTER INVESTIGATION
ADVERSE REACTIONS TO PRESCRIBED DRUGS IN THE ELDERLY - A MULTICENTER INVESTIGATION
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DOI：
10.1093/ageing/9.2.73
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发表时间：
1980-01-01
期刊：
影响因子：
6.7
通讯作者：
CHOPIN, JM
中科院分区：
文献类型：
--
作者：
WILLIAMSON, J;CHOPIN, JM
在英格兰、威尔士和苏格兰[英国]1975-1976年间连续入院的1998名患者中，81.3%的患者在入院时正在接受处方药物治疗。有248例患者出现不良反应，占处方吸毒者的15.3%。在这些患者中，有209人被认为是不良反应导致需要入院治疗。68%的患者从不良反应和后遗症中完全恢复。降压药、抗帕金森病药物和精神药物的不良反应风险最大，尽管最多的不良反应(60例)是由利尿剂引起的，利尿剂是迄今为止最常见的处方药物(占样本的37.4%)。
Of 1998 patients consecutively admitted to geriatric medicine departments in England, Wales and Scotland [UK] in 1975-1976, 81.3% were receiving prescribed drugs at time of admission. Adverse reactions were noted in 248 patients, representing 15.3% of prescribed drug takers. In 209 of these patients, it was thought that an adverse reaction had contributed to the need for admission to hospital. Full recovery from adverse reactions and sequelae occurred in 68% of those with such reactions. Hypotensive drugs, antiparkinsonian drugs and psychotropics carried the greatest risk of adverse reactions, although the largest single number of adverse reactions (60) were due to diuretics which were by far the most commonly prescribed drugs (37.4% of sample).