Cognitive and motor development among small-for-gestational-age infants: Impact of zinc supplementation, birth weight, and caregiving practices
Cognitive and motor development among small-for-gestational-age infants: Impact of zinc supplementation, birth weight, and caregiving practices
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DOI：
10.1542/peds.113.5.1297
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发表时间：
2004-05-01
期刊：
影响因子：
8
通讯作者：
Menon, V
中科院分区：
文献类型：
--
作者：
Black, MM;Sazawal, S;Menon, V
Objective.出生时小于胎龄儿（SGA）的婴儿有发育迟缓的风险，这可能与锌（一种必需的微量金属）缺乏有关，也可能与他们引起照顾者反应的能力不足有关（功能性隔离假说）。本研究的目的是评估在6个月和10个月大时，为期9个月的5 mg锌补充试验对出生SGA的婴儿的发育和行为的影响，并评估婴儿引起响应性照顾者行为的能力。在印度德里的一个低收入城市社区的200名婴儿中进行了一项补充锌的随机对照试验。婴儿在足月（>36周）和SGA（出生体重）时被招募
Objective. Infants who are born small for gestational age (SGA) are at risk for developmental delays, which may be related to deficiencies in zinc, an essential trace metal, or to deficiencies in their ability to elicit caregiver responsiveness (functional isolation hypothesis). The objective of this study was to evaluate at 6 and 10 months of age the impact of a 9-month supplementation trial of 5 mg of zinc on the development and behavior of infants who were born SGA and to evaluate infants' ability to elicit responsive caregiver behavior.Methods. A randomized, controlled trial of zinc supplementation was conducted among 200 infants in a low-income, urban community in Delhi, India. Infants were recruited when they were full term (>36 weeks) and SGA (birth weight