Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction - Two-year findings from the Oregon sudden unexpected death study
Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction - Two-year findings from the Oregon sudden unexpected death study
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DOI：
10.1016/j.jacc.2005.11.045
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发表时间：
2006-03-21
影响因子：
24
通讯作者：
Chugh, SS
中科院分区：
文献类型：
--
作者：
Stecker, EC;Vickers, C;Chugh, SS
我们试图评估左心室（LV）功能障碍对发生心脏性猝死（SCD）在一般人群中的贡献，并确定在没有LV功能障碍的情况下SCD的显著特征。背景表现出警告症状和体征的患者更有可能在SCD前接受评估。尽管该亚组中LV功能障碍的患病率可能高估了总体SCD的患病率，但这是一般人群中唯一的评估方法。方法：俄勒冈州穆特诺玛县（人口660，486; 2002 - 2004）的所有SCD病例均在正在进行的俄勒冈州意外猝死研究中前瞻性确定。我们回顾性评估了SCD前接受LV功能评价的受试者的LV射血分数（LVEF）（正常：>= 55%;轻度至中度降低：36%至54%;重度降低：
OBJECTIVES We sought to evaluate the contribution of left ventricular (LV) dysfunction toward occurrence of sudden cardiac death (SCD) in the general population, and to identify distinguishing characteristics of SCD in the absence of LV dysfunction.BACKGROUND Patients who manifest warning symptoms and signs are more likely to undergo evaluation before SCD. Although prevalence of LV dysfunction in this subgroup may overestimate the prevalence in overall SCD, this is the only means of assessment in the general population. METHODS All cases of SCD in Multnomah County, Oregon (population 660,486; 2002 to 2004) were prospectively ascertained in the ongoing Oregon Sudden Unexpected Death Study. We retrospectively assessed LV ejection fraction (LVEF) among subjects who underwent evaluation of LV function before SCD (normal: >= 55%; mildly to moderately reduced: 36% to 54%; and severely reduced: