The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer.
The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer.
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DOI：
10.18632/oncotarget.24309
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发表时间：
2018-02-09
期刊：
影响因子：
--
通讯作者：
Lee SS
中科院分区：
文献类型：
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作者：
Chakraborty C;Sharma AR;Sharma G;Sarkar BK;Lee SS
医生推荐联合治疗癌症的各种优势。由于联合疗法在癌症治疗中具有协同作用，因此可以提高治疗效果。在这个后基因组时代，microRNAs（miRNAs）因其在人类疾病和疾病治疗中的作用而受到关注。在这篇综述中，我们讨论了miRNA和化疗药物的组合用于癌症治疗。此外，我们试图描绘miRNA在癌症治疗中的作用;概述联合治疗，特别是化疗联合治疗，并讨论基于miRNA的化疗联合治疗和miRNA化疗联合治疗癌症的基础。
Medical practitioners are recommending combination therapy in cancer for its various advantages. Combination therapy increases the efficacy of treatment due to its synergistic effects in cancer treatment. In this post-genomic era, microRNAs (miRNAs) are receiving attention for their role in human disease and disease therapy. In this review, we discuss the combination of miRNAs and chemotherapeutic agents for cancer treatment. Moreover, we attempted to portray the role of miRNAs in cancer therapy; outline combination therapy, especially chemo-combination therapy, and discuss the basis for miRNA-based chemo-combination therapies and chemo-combination therapy with miRNA for cancer treatment.