Transient suppression of tinnitus by transcranial magnetic stimulation
Transient suppression of tinnitus by transcranial magnetic stimulation
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DOI：
10.1002/ana.10468
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发表时间：
2003-02-01
影响因子：
11.2
通讯作者：
Gerloff, C
中科院分区：
文献类型：
--
作者：
Plewnia, C;Bartels, M;Gerloff, C
耳鸣是一种常见的神经性疾病，耳鸣的发生与耳鸣的发生有关。如果这种活动是耳鸣相关网络的功能相关组成部分，则该区域的虚拟临时损伤应导致耳鸣的短暂减少。为了验证这一假设，我们对14名慢性耳鸣患者的8个头皮和4个控制位置施加10 Hz重复经颅磁刺激。刺激左颞顶皮层显著降低耳鸣（弗里德曼方差分析，p < 0.05;与对照组相比），表明次级听觉区可能对耳鸣感知至关重要，可能是适应不良的皮层重组的结果。
It has been proposed that tinnitus is associated with an irregular activation of the temporoparietal cortex. If this activity is a functionally relevant component of the tinnitus-related network, a virtual temporary lesion of this area should result in transient reduction of tinnitus. To test this hypothesis, we applied 10Hz repetitive transcranial magnetic stimulation to eight scalp and four control positions in 14 patients with chronic tinnitus. Stimulation of left temporoparietal cortex significantly reduced tinnitus (Friedman analysis of variance, p < 0.05; compared with control), indicating that secondary auditory areas can be critical for tinnitus perception, perhaps as a consequence of maladaptive cortical reorganization.