Electrically Controlled Nanofluidic DNA Sluice for Data Storage Applications
Electrically Controlled Nanofluidic DNA Sluice for Data Storage Applications
复制标题
DOI：
10.1021/acsanm.1c02519
复制
发表时间：
2021-10-12
影响因子：
5.9
通讯作者：
Leburton, Jean-Pierre
中科院分区：
文献类型：
--
作者：
Athreya, Nagendra;Khandelwal, Apratim;Leburton, Jean-Pierre
我们为基于DNA的数据存储设备的电控制纳米流体槽的高级体系结构提出了一个高级体系结构。我们的设备包括嵌入的金电极，将适当的电压用于有效捕获，保持和释放的嵌合DNA链。通过多物理模拟获得的设备跨设备的静电概况，该模拟求解了Nernst-Planck-Poisson方程，显示了两种设备架构的纳米级缝隙操作：一个带有平面电极的静电性，另一个带有埋入的拱形电极与平面电极结合使用。我们的模拟表明，除了它与互补金属氧化物 - 氧化物 - 官方导体（CMOS）技术外，具有埋入拱形电极的设备体系结构还可以有效地存储嵌合DNA链，而无需泄漏，同时释放，同时提供大规模的功能一体化。
We propose an advanced architecture of an electrically controlled nanofluidic sluice for a DNA-based data storage device. Our device comprises embedded gold electrodes to which appropriate voltages are applied for effective capture, hold, and release of chimeric DNA strands. Electrostatic potential profiles across the device obtained via multiphysics simulation that solves for the Nernst-Planck-Poisson equation show nanoscale sluice operation for two device architectures: one with planar electrodes and the other with buried arch electrodes in combination with planar electrodes. Our simulations show that apart from its compatibility with complementary metal oxide-semiconductor (CMOS) technology, the device architecture with buried arch electrodes can effectively store the chimeric DNA strands without any leakage in conjunction with release on demand while offering the capability for large-scale integration.