Anaphylactic symptoms due to chlorhexidine gluconate.
Anaphylactic symptoms due to chlorhexidine gluconate.
复制标题
葡萄糖酸氯己定引起的过敏症状。
DOI：
10.1001/archderm.1989.01670130052005
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发表时间：
1989
影响因子：
--
通讯作者：
T. Aoki
中科院分区：
文献类型：
--
作者：
M. Okano;M. Nomura;S. Hata;N. Okada;K. Sato;Y. Kitano;M. Tashiro;Y. Yoshimoto;R. Hama;T. Aoki
六名病人谁开发荨麻疹，呼吸困难，过敏性休克，由于局部应用葡萄糖酸氯己定溶液进行了描述。葡萄糖酸氯己定通过皮内、划痕和表皮试验证实为I型超敏反应的病原体。为了防止危及生命的不良反应，按照生产商的建议，在伤口表面使用浓度为0.05%的葡萄糖酸氯己定似乎很重要;葡萄糖酸氯己定可能不适合用于粘膜。
Six patients who developed urticaria, dyspnea, and anaphylactic shock due to topical application of chlorhexidine gluconate solution are described. Chlorhexidine gluconate was confirmed as the causative agent of type I hypersensitivity by intradermal, scratch, and epicutaneous tests. To prevent life-threatening adverse reactions, it seems important to use chlorhexidine gluconate on wound surfaces at a concentration of 0.05%, as recommended by the manufacturer; chlorhexidine gluconate may not be suitable for application to mucous membranes.