Trends in antibiotic prescribing by dental practitioners in Germany
Trends in antibiotic prescribing by dental practitioners in Germany
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DOI：
10.1016/j.jcms.2017.08.010
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发表时间：
2017-11-01
影响因子：
3.1
通讯作者：
Ziebart, Thomas
中科院分区：
文献类型：
--
作者：
Halling, Frank;Neff, Andreas;Ziebart, Thomas
目的：分析德国4年间牙科医生抗菌药物处方结构与医用抗生素处方的关系。材料与方法：收集2012年至2015年全国所有法定医保牙科系统抗菌药物处方数据。“地方保健系统研究所”(WIdO，柏林)的年度报告为这一纵向数据库分析提供了基础。分析抗菌药物的种类、处方数和限定日剂量(DDD)。结果：平均每年有8.8%的抗生素处方是由牙医开出的。处方最多的抗生素是阿莫西林。阿莫西林在所有牙科处方中的比例从2012年的35.6%上升到2015年的45.8%(p<；0.01)。大约四分之三的牙科用药DDD可以归因于阿莫西林和克林霉素。医生使用克林霉素的比例比牙科低18倍。结论：德国牙科和医用抗生素处方在抗生素处方中所占比例存在显著差异。在国际比较中，克林霉素在德国的高比例是值得注意的。(C)2017年欧洲颅颌面部外科协会。爱思唯尔有限公司出版。保留所有权利。
Purpose: To analyze the structure of antibiotic prescriptions by dentists in Germany during a time-period of four years in relation to medical antibiotic prescriptions.Materials and methods: We collected nationwide data from all statutory health insurances on dental prescriptions of systemic antibiotics from 2012 to 2015. The annual reports of the "Research Institute for Local Health Care Systems" (WIdO, Berlin) provided the basis for this longitudinal data base analysis. The types of antibiotics, the number of prescriptions and the prescribed ' defined daily doses' (DDD) were analyzed. The results were compared to antibiotic prescriptions of German physicians.Results: An average of 8.8% per year of all antibiotic prescriptions is issued by dentists. The mostly prescribed antibiotic is amoxicillin. The share of amoxicillin on all dental prescriptions increased from 35.6% in 2012 to 45.8% in 2015 (p < 0.01). About three-quarters of all dentally prescribed DDD can be attributed to amoxicillin and clindamycin. On the part of the physicians the proportion of clindamycin is 18 fold lower than in the dental field.Conclusions: Dental and medical antibiotic prescriptions in Germany show statistically significant differences regarding the shares of the prescribed antibiotics. In an international comparison the high proportion of Clindamycin in Germany is noticeable. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.