Enantio- and Diastereocontrolled Total Synthesis of (+)-Strictifolione
Enantio- and Diastereocontrolled Total Synthesis of (+)-Strictifolione
复制标题
DOI:
10.1002/ejoc.201001221
复制
发表时间:
2010-12-01
影响因子:
2.8
通讯作者:
Dhavale, Dilip D.
中科院分区:
文献类型:
--
作者:
Kumar, Pradeep;Pandey, Menaka;Dhavale, Dilip D.
A concise and practical enantioselective synthesis of (+)-strictifolione has been achieved in high diastereomeric excess using Jacobsen's hydrolytic kinetic resolution, proline-catalyzed sequential alpha-aminoxylation and Horner-Wadsworth-Emmons olefination of aldehyde and cross olefin/ring-closing metathesis as the key steps.