Recent advances from application of doubly labeled water to measurement of human energy expenditure
Recent advances from application of doubly labeled water to measurement of human energy expenditure
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DOI：
10.1093/jn/129.10.1765
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发表时间：
1999-10-01
影响因子：
4.2
通讯作者：
Schoeller, DA
中科院分区：
文献类型：
--
作者：
Schoeller, DA
双标记水(DLW)方法是在50年前开发出来的，但近40年后它才成为人类营养研究的主要工具。然而，自从第一次人类应用以来，它的使用已经戏剧性地增长。DLW方法现在是确定健康和临床人群能量需求的首选方法。该方法已被广泛应用于日益严重的肥胖问题的研究，以确定能量消耗和体力活动在体重控制中的作用。最后，DLW提供了一种新的方法来验证评估膳食摄入量的方法。DLW方法的准确性和非侵入性使其成为研究人体能量代谢的理想方法。
The doubly labeled water (DLW) method was developed 50 years ago, but nearly 40 years passed before it became a major tool for human nutrition research. Its use has grown dramatically, however, since the first human applications. The DLW method is now the preferred method for determining energy requirements of healthy and clinical populations. The method has been applied extensively to the study of the growing problem of obesity in order to determine the role of energy expenditure and physical activity in weight control. Finally, DLW has provided a new means of validating methods for assessing dietary intake. The accuracy and noninvasive nature of the DLW method makes it ideal for the study of human energy metabolism.