In-field radiation contamination during intraoperative electron radiation therapy with a dedicated accelerator
In-field radiation contamination during intraoperative electron radiation therapy with a dedicated accelerator
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DOI：
10.1016/j.apradiso.2019.108918
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发表时间：
2020-01-01
影响因子：
1.6
通讯作者：
Aminafshar, Behzad
中科院分区：
文献类型：
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作者：
Baghani, Hamid Reza;Aminafshar, Behzad
本研究定量评价了术中专用电子放疗加速器LIAC12在不同电子能量（6-12 MeV）和施加器尺寸（3、5和10 cm直径）下产生的场内辐射污染，包括光子和中子。为此，采用了经过验证的LIAC12头部MC模型，并结合不同的涂抹器直径。结果表明，场内光子污染的影响高度依赖于电子能量和场尺寸，随着电子能量的增加和场尺寸的减小，场内光子污染的影响分别增加约3倍和10倍。只有在12 MeV的电子能量下才发现中子污染，在更低的电子能量下获得零中子通量。当施加器直径从10 cm减小到3 cm时，中子污染的影响增加了约7倍。每递送1 Gy电子剂量的最大中子剂量和光子剂量分别约为0.3 μ Sv和7.24 mSv。该专用IOERT加速器产生的中子污染比传统放射治疗加速器产生的中子污染低约10（-3）倍。
The in-field radiation contamination including photons and neutrons originated from a dedicated intraoperative electron radiotherapy (IOERT) accelerator, LIAC12, at different electron energies (6-12 MeV) and applicator sizes (3, 5 and 10 cm diameter) were quantitatively evaluated in the current study. A validated MC model of LIAC12 head in conjunction with different applicator diameters was employed for this purpose. The results showed that the fluence of in-field photon contamination is highly dependent on the electron energy and field size so that it would be increased by the factors of about 3 and 10 with an increment of electron energy and decrement of field size, respectively. Neutron contamination was found only at 12 MeV electron energy and zero neutron fluence was obtained at lower electron energies. The same trend with the field size was observed for neutron contamination fluence that increased about 7 times by decreasing the applicator diameter from 10 cm to 3 cm. The maximum contaminant neutron dose and photon dose per one Gy delivered electron dose were obtained about 0.3 mu Sv and 7.24 mSv, respectively. The produced neutron contamination by this dedicated IOERT accelerator was approximately 10(-3) times lower than those originated from a conventional radiotherapy accelerator.