The learning ability and motility of senescence accelerated mice (SAM‐P/1) treated with Toki‐Shakuyaku‐San
The learning ability and motility of senescence accelerated mice (SAM‐P/1) treated with Toki‐Shakuyaku‐San
复制标题
Toki-Shakuyaku-San 治疗加速衰老小鼠 (SAM-P/1) 的学习能力和运动能力
DOI：
10.1002/ptr.2650070719
复制
发表时间：
1993
影响因子：
7.2
通讯作者：
M. Iseki
中科院分区：
文献类型：
--
作者：
M. Kishikawa;Mika Nishimura;M. Sakae;M. Iseki
研究汉方药物Toki-Shakuyaku-San对小鼠运动和学习能力的影响。给药15周后，对5月龄小鼠进行的试验显示自发运动无变化。然而，在一项采用被动回避任务的学习能力研究中，Toki‐Shakuyaku‐San给药组的测试潜伏期明显长于对照组，表明Toki‐Shakuyaku‐San可能在缓解小鼠学习障碍方面发挥了一定作用。
The effects of the Kampo medicine Toki‐Shakuyaku‐San on the motility and learning ability of mice were studied. An assay on mice aged 5 months after 15 weeks of administration revealed no change in spontaneous motility. However, in a study on learning ability employing passive avoidance task, the latent periods of test trial were significantly longer in the Toki‐Shakuyaku‐San administered group than in a control group, indicating that Toki‐Shakuyaku‐San may play some role in the alleviation of learning disturbances in mice.