Reticular formation activity during wakefulness and sleep in a hibernator (Spermophilus lateralis).
Reticular formation activity during wakefulness and sleep in a hibernator (Spermophilus lateralis).
复制标题
冬眠者清醒和睡眠期间的网状形成活动（侧生精子）。
DOI：
10.1016/0006-8993(91)90516-x
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发表时间：
1991
期刊：
影响因子：
2.9
通讯作者：
Heller,HC
中科院分区：
文献类型：
--
作者：
Krilowicz,BL;Edgar,DM;Heller,HC
本研究检查了地松鼠网状结构（RF）细胞活性作为以下功能的函数：（1）唤醒状态，以及（2）颈部肌肉活动的阶段性变化。从11只行为松鼠（Spermophilus lateralis）中共记录了37个神经元。5个细胞位于中脑RF，15个位于涉及运动输出抑制的外侧脑桥部位，即蓝斑下区域，11个位于内侧脑桥RF，6个位于延髓RF。无论位置如何，大多数细胞（81%; 37个中的30个）在动物清醒和/或快速眼动（REM）睡眠时表现出最大的活性。然而，神经元活动和颈部肌肉活动的阶段性变化之间的关系不同的位置的功能。53%的细胞（15个中的8个）位于蓝斑下区域的活动增加，肌电图（EMG）活动的阶段性下降，而其他RF站点的细胞（22个中的22个）的活动减少或没有改变，肌电图活动的阶段性下降。在颈部肌肉活动的阶段性下降过程中，蓝斑下区细胞的活动增加进一步表明，脑桥外侧RF参与促进REM睡眠和可能的觉醒过程中的肌肉弛缓。
This study examined ground squirrel reticular formation (RF) cell activity as a function of: (1) arousal state, and, (2) phasic alterations in neck muscle activity. A total of 37 neurons were recorded from 11 behaving squirrels (Spermophilus lateralis). Five cells were located in the midbrain RF, 15 were in the lateral pontine site implicated in inhibition of motor output, i.e. the subcoeruleus area, 11 were in the medial pontine RF, and 6 were in the medullary RF. Regardless of location, the majority of the cells (81%; 30 of 37) exhibited greatest activity when the animals were awake and/or in rapid-eye-movement (REM) sleep. However, the relationship between neuronal activity and phasic alterations in neck muscle activity differed as a function of location. The activity of 53% of cells (8 of 15) located in the subcoeruleus area increased with phasic decreases in electromyographic (EMG) activity, whereas the activity of cells (22 of 22) in other RF sites decreased or did not change with phasic decreases in EMG activity. The increased activity of subcoeruleus area cells during phasic decreases in neck muscle activity is further evidence suggesting that the lateral pontine RF is involved in promotion of muscle atonia during REM sleep and possibly wakefulness.