Accelerated multi-contrast high isotropic resolution 3D intracranial vessel wall MRI using a tailored k-space undersampling and partially parallel reconstruction strategy
Accelerated multi-contrast high isotropic resolution 3D intracranial vessel wall MRI using a tailored k-space undersampling and partially parallel reconstruction strategy
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DOI：
10.1007/s10334-018-0730-8
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发表时间：
2019-06-01
影响因子：
2.3
通讯作者：
Yuan, Chun
中科院分区：
文献类型：
--
作者：
Balu, Niranjan;Zhou, Zechen;Yuan, Chun
目的建立一种各向同性分辨率为0.5mm、每次扫描时间为5 min的三维多对比度IVW方案。材料与方法对比前T1 w VISTA、DANTE制备的PDw VISTA、SNAP和对比后T1 w VISTA分别采用CARDON欠采样靶点排序法（CUSTOM）和自支持定制k空间估计并行成像重建（STEP）进行加速。在正常志愿者和颅内动脉粥样硬化性疾病（ICAD）受试者中，将CUSTOM+STEP IVW与全样本IVW、SENSE加速IVW和CUSTOM+零填充傅立叶重建进行了比较。图像质量，血管描绘，CSF抑制，和血液抑制compared.ResultsCUSTOM+STEP血管壁描绘是可比的全样本IVW和更好的比SENSE IVW的血管壁描绘T1 w VISTA和管腔对比SNAP。与零填充傅立叶重建相比，使用STEP重建的平均图像质量和壁描绘显着改善，CSF或血液抑制无显着差异。结论CUSTOM +STEP允许在30分钟内实现多对比3D 0.5 mm各向同性IVW。尽管CUSTOM-STEP的一些定量和定性评分低于全样本IVW，但CUSTOM+STEP提供的血管壁描绘与全样本IVW相当，且上级SENSE。CUSTOM+STEP IVW在患者中耐受性良好，并显示出良好的ICAD斑块轮廓。
ObjectiveTo develop a 3D multi-contrast IVW protocol with 0.5-mm isotropic resolution and a scan time of 5min per sequence.Materials and methodsPre-contrast T1w VISTA, DANTE prepared PDw VISTA, SNAP, and post-contrast T1w VISTA were accelerated using cartesian undersampling with target ordering method (CUSTOM) and self-supporting tailored k-space estimation for parallel imaging reconstruction (STEP). CUSTOM+STEP IVW was compared to full-sample IVW, SENSE-accelerated IVW, and CUSTOM+zero-filled Fourier reconstruction in normal volunteers and subjects with intracranial atherosclerotic disease (ICAD). Image quality, vessel delineation, CSF suppression, and blood suppression were compared.ResultsCUSTOM+STEP vessel wall delineation was comparable to full-sample IVW and better than SENSE IVW for vessel wall delineation on T1w VISTA and luminal contrast on SNAP. Average image quality and wall depiction were significantly improved using STEP reconstruction compared with zero-filled Fourier reconstruction, with no significant difference in CSF or blood suppression.ConclusionsCUSTOM+STEP allowed multi-contrast 3D 0.5-mm isotropic IVW within 30min. Although some quantitative and qualitative scores for CUSTOM-STEP were lower than fully sampled IVW, CUSTOM+STEP provided comparable vessel wall delineation as full-sample IVW and was superior to SENSE. CUSTOM+STEP IVW was well tolerated by patients and showed good delineation of ICAD plaque.