Structure of the Epstein-Barr virus nuclear antigen as probed with monoclonal antibodies.
Structure of the Epstein-Barr virus nuclear antigen as probed with monoclonal antibodies.
复制标题
用单克隆抗体探测 Epstein-Barr 病毒核抗原的结构。
DOI：
10.1016/0042-6822(85)90436-2
复制
发表时间：
1985
期刊：
影响因子：
3.7
通讯作者：
Levine,AJ
中科院分区：
文献类型：
--
作者：
Hearing,JC;Lewis,A;Levine,AJ
已分离出五种分泌针对EB病毒（EBV）核抗原（BamHI K抗原）的抗体的杂交瘤细胞系。所有五种抗体都能在多种EBV阳性淋巴母细胞系中检测到这种抗原。这些抗体与该蛋白质的几种突变形式的反应允许预测抗体结合位点。
Five hybridoma cell lines secreting antibodies directed against an Epstein-Barr virus (EBV) nuclear antigen (BamHI K antigen) have been isolated. All five antibodies detect this antigen in a variety of EBV-positive lymphoblastoid cell lines. The reaction of these antibodies with several mutant forms of this protein has allowed the antibody binding site(s) to be predicted.