P-3 latency change in aging and Parkinson disease
P-3 latency change in aging and Parkinson disease
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DOI：
10.1001/archneur.1997.00550150054016
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发表时间：
1997-03-01
影响因子：
--
通讯作者：
Sugita, M
中科院分区：
文献类型：
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作者：
Tachibana, H;Aragane, K;Sugita, M
目的：评估帕金森病（PD）患者的事件相关电位评估的年龄相关的心理加工减慢是否比年龄匹配的对照组更显著。设计：PD患者和年龄匹配的对照组的连续病例系列。设置：日本西宫的一所大学医院。研究参与者：28名非痴呆的PD患者和28名年龄匹配的对照组。主要结果测量：事件相关电位的P-3成分在视觉语义辨别任务中被引出。用相关和回归分析评价各组P-3潜伏期和反应时（RT）与年龄的关系。P-3）潜伏期、RT和年龄之间的关系也通过将两组分为年轻组（年龄
Objective: To evaluate whether age-related slowing of mental processing assessed by event-related potentials is more prominent in patients with Parkinson disease (PD) than in age-matched control subjects.Design: Consecutive case series of patients with PD and an age-matched control group.Setting: A university hospital in Nishinomiya, Japan.Study Participants: Twenty-eight nondemented patients with PD and 28 age-matched control subjects.Main Outcome Measures: The P-3 component of the event-related potentials was elicited during a visual semantic discrimination task. The relation of the P-3 latency and the reaction time (RT) to age within each group was evaluated using correlation and regression analysis. The relationship among the P-3) latency, the RT, and age was also assessed by dividing both groups into younger (age