Association between alcoholic beverage consumption and incidence of coronary heart disease in whites and blacks - The Atherosclerosis Risk in Communities Study
Association between alcoholic beverage consumption and incidence of coronary heart disease in whites and blacks - The Atherosclerosis Risk in Communities Study
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DOI：
10.1093/aje/kwh229
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发表时间：
2004-09-01
影响因子：
5
通讯作者：
Szklo, M
中科院分区：
文献类型：
--
作者：
Fuchs, FD;Chambless, LE;Szklo, M
作者评估了社区动脉粥样硬化风险研究中白人和非裔美国人参与者的酒精饮料消费与冠心病发病率之间的关系。 1987 年至 1998 年间的平均随访时间为 9.8 年。通过 Cox 比例风险回归模型对这种关联进行了分析。作者发现，黑人男性的乙醇消耗量与冠心病发病率呈正相关（乙醇消耗量每天增加 13 克，调整后的风险比 (HR) = 1.13，95% 置信区间 (CI)：1.01, 1.28），而白人男性则呈负相关（HR = 0.88，95% CI：0.79, 0.99）。在白人女性中，冠心病与很少饮酒（HR = 0.47，95% CI：0.28，0.80）、每周饮酒量大于或等于 70 克（HR = 0.49，95% CI：0.24，0.98）以及每周饮酒量大于或等于 210 克（HR = 0.56，95% CI： 0.33, 0.95) 在白人中。在黑人男性中，该关联对 140-
The authors evaluated the relation between consumption of alcoholic beverages and incidence of coronary heart disease in White and African-American participants in the Atherosclerosis Risk in Communities Study. The average duration of follow-up was 9.8 years between 1987 and 1998. The association was analyzed by means of Cox proportional hazards regression models. The authors found a positive association between ethanol consumption and incident coronary heart disease for Black men (for a 13-g/day increment in ethanol consumption, adjusted hazard ratio (HR) = 1.13, 95% confidence interval (CI): 1.01, 1.28) and an inverse association for White men (HR = 0.88, 95% CI: 0.79, 0.99). There was an inverse association of coronary heart disease with rare drinking (HR = 0.47, 95% CI: 0.28, 0.80) and with consumption of greater than or equal to70 g of ethanol per week (HR = 0.49, 95% CI: 0.24, 0.98) in White women and with consumption of greater than or equal to210 g/week (HR = 0.56, 95% CI: 0.33, 0.95) in White men. In Black men, the association was positive for consumption of 140-