Greater functional connectivity between reading and error-detection regions following training with the reading acceleration program in children with reading difficulties
Greater functional connectivity between reading and error-detection regions following training with the reading acceleration program in children with reading difficulties
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DOI：
10.1007/s11881-015-0096-9
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发表时间：
2015-04-01
影响因子：
2.3
通讯作者：
Holland, Scott K.
中科院分区：
文献类型：
--
作者：
Horowitz-Kraus, Tzipi;Holland, Scott K.
阅读加速计划是一项计算机化计划，旨在改善阅读困难（RD）和典型阅读者（TR）的阅读和错误检测机制的激活。本研究的目的是使用功能连接分析，在讲英语的8-12岁RD和TR儿童中找到这种效应的神经相关性。功能磁共振成像数据收集在词汇决策任务前后4周的培训计划，连同阅读和执行功能的措施。结果表明RD儿童的阅读、视觉注意力和处理速度得到改善。训练后，观察到更大的功能连接之间的左梭状回和右前扣带皮层的RD儿童和左梭状回和左前扣带皮层之间的TR。训练后功能连接的变化与两组中文字阅读和视觉注意力的行为评分增加相关。研究结果支持了先前的研究结果，即RD和TR儿童在接受阅读加速计划训练后，监测和心理词汇得到了改善。本文还讨论了RD儿童前扣带皮层偏侧性的差异以及扣带-盖控制网络在语言处理中的可能作用。
The Reading Acceleration Program is a computerized program that improves reading and the activation of the error-detection mechanism in individuals with reading difficulty (RD) and typical readers (TRs). The current study aims to find the neural correlates for this effect in English-speaking 8-12-year-old children with RD and TRs using a functional connectivity analysis. Functional magnetic resonance imaging data were collected during a lexical decision task before and after 4 weeks of training with the program, together with reading and executive functions measures. Results indicated improvement in reading, visual attention, and speed of processing in children with RD. Following training, greater functional connectivity was observed between the left fusiform gyrus and the right anterior cingulate cortex in children with RD and between the left fusiform gyrus and the left anterior cingulate cortex in TRs. The change in functional connectivity after training was correlated with increased behavioral scores for word reading and visual attention in both groups. The results support previous findings of improved monitoring and mental lexicon after training with the Reading Acceleration Program in children with RD and TRs. The differences in laterality of the anterior cingulate cortex in children with RD and the presumable role of the cingulo-opercular control network in language processing are discussed.