Determinants of quality of life for patients with kidney stones
Determinants of quality of life for patients with kidney stones
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DOI：
10.1016/j.juro.2008.01.116
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发表时间：
2008-06-01
影响因子：
6.6
通讯作者：
Lotan, Yair
中科院分区：
文献类型：
--
作者：
Bensalah, Karim;Tuncel, Altug;Lotan, Yair
目的：我们评估了各种因素与生活质量在人口中的患者stone.Materials和方法：共155例患者在我们的泌尿科门诊结石1月至2007年5月之间进行了前瞻性询问关于结石的历史，并管理SF-36（TM）问卷，以评估生活质量。从患者那里获得了年龄、体重指数、美国麻醉医师协会评分、结石发作次数、距上次结石发作的间隔时间、结石手术次数和相关并发症、缺勤天数和长期医疗情况。个体SF-36领域和综合评分与美国普通人群进行比较。进行单变量和多变量回归分析，以评估所有协变量对生活质量scores.Results的影响：结石患者得分低于平均美国人口在5的SF-36的8个领域，以及在物理综合评分。多变量回归模型显示，增加身体质量指数和年龄是身体健康下降的最强预测因素。结石发作次数不影响SF-36评分，尽管外科手术次数影响身体和精神成分。输尿管镜手术和支架置入的数量主要影响心理健康。药物治疗，特别是柠檬酸钾的使用，与更有利的quality of life.Conclusions：各种因素影响尿石症患者的生活质量，但最重要的是体重指数，年龄和手术次数。前瞻性纵向研究可能会进一步阐明生活质量的决定因素，他们可能会被用来优化病人的护理。
Purpose: We evaluated various factors relating to quality of life in a population of patients with stones.Materials and Methods: A total of 155 patients seen at our urology clinic for stones between January and May 2007 were prospectively questioned regarding stone history and were administered the SF-36 (TM) questionnaire to assess quality of life. Age, body mass index, American Society of Anesthesiologists score, number of stone episodes, interval from the last stone episode, number of surgical procedures for stones and associated complications, missed days of work and long-term medical treatment were elicited from the patients. Individual SF-36 domains and composite scores were compared to those of the American general population. Univariate and multivariate regression analyses were performed to assess the impact of all covariates on quality of life scores.Results: Patients with stones scored lower than the average American population in 5 of the 8 domains of the SF-36 as well as in the physical composite score. Multivariate regression modeling showed that increasing body mass index and age were the strongest predictors of decreased physical well-being. The number of stone episodes did not influence SF-36 scores, although the number of surgical procedures impacted physical and mental components. The number of ureteroscopy procedures and stent placements primarily impacted mental well-being. Medical therapy, particularly the use of potassium citrate, was associated with more favorable quality of life.Conclusions: Various factors impact quality of life in patients with urolithiasis but the most important are body mass index, age and the number of surgical procedures. Prospective longitudinal studies may further elucidate the determinants of quality of life and they might be used to optimize patient care.