Core-Shell Structured PEO-Chitosan Nanofibers by Coaxial Electrospinning
Core-Shell Structured PEO-Chitosan Nanofibers by Coaxial Electrospinning
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DOI：
10.1021/bm201444v
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发表时间：
2012-02-01
影响因子：
6.2
通讯作者：
Ajji, Abdellah
中科院分区：
文献类型：
--
作者：
Pakravan, Mehdi;Heuzey, Marie-Claude;Ajji, Abdellah
使用同轴静电纺丝装置 PEO 和壳聚糖生产了核壳结构的 PEO-壳聚糖纳米纤维。两种溶液均在乙酸水溶液中，分别用作内层（核）和外层（壳）。生产出直径为 150-190 nm 的尺寸均匀、无缺陷的纳米纤维。此外，还可以得到中空纳米纤维。 PEO 清洗膜。通过洗涤含水 PEO 之前和之后获得的 TEM 图像证实了核壳纳米结构和壳层上壳聚糖的存在。XPS 研究进一步支持了复合纳米纤维表面壳聚糖的存在。通过 TGA 分析测定了纳米纤维垫中的壳聚糖和 PEO 组成，其比例与它们在进料溶液中的比例相似。膜的局部组成均匀性以及去除 PEO 的洗涤步骤的效率也通过 FTIR 进行了验证。此外，还使用 DSC 和 XRD 来表征共静电纺非织造垫的晶体结构和形貌。由于外表面存在壳聚糖，所制备的同轴纳米纤维（空心和实心）具有多种潜在的应用。
Core-shell structured PEO-chitosan nanofibers have been produced using a coaxial electrospinning setup PEO and chitosan. solutions, both in an aqueous acetic acid solvent, were used as the inner (core) and outer (shell) layer, respectively. Uniform-sized defect-free nanofibers of 150-190 nm diameter were produced. In addition, hollow nanofibers could be obtained subsequent to,. PEO washing of the membranes. The core-shell nanostructure and existence of chitosan on the shell layer were confirmed by TEM images obtained before and after washing the PEO, content with water., The presence of chitosan on the surface of the composite nanofibers was further supported by XPS studies. The chitosan and PEO compositions in the nanofibrous mats were determined by TGA analysis, which were similar to their ratio in the feed solutions, The local compositional homogeneity of the membranes and the efficiency of the washing step to remove PEO were also verified by FTIR. In addition, DSC and XRD were used to characterize the crystalline structure and morphology of the co-electrospun nonwoven mats. The prepared coaxial nanofibers (hollow and solid) have several potential applications due to the presence of chitosan on their outer surfaces.