Neural effects of visualizing and perceiving aversive stimuli: A PET investigation
Neural effects of visualizing and perceiving aversive stimuli: A PET investigation
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DOI：
10.1097/00001756-199607080-00007
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发表时间：
1996-07-08
期刊：
影响因子：
1.7
通讯作者：
Alpert, NM
中科院分区：
文献类型：
--
作者：
Kosslyn, SM;Shin, LM;Alpert, NM
当中年受试者观看或可视化中性或厌恶刺激的图片时，记录脑血流量（使用正电子发射断层扫描），然后确定听觉呈现的陈述是否正确描述了刺激。相对于可视化中性刺激，可视化厌恶性刺激增强了第 17 区（右）和第 18 区（双侧）以及前岛叶（双侧）和中额叶皮层（左）的脑血流量。区域 17 和区域 18 已被确定为支持意象体验基础的表征，而前岛叶是自主神经系统输入的主要皮质接收器。相对于中性刺激，感知厌恶刺激增强了 46 区、角回、19 区、47 区和颞中回（均位于左半球）的脑血流量。所有这些领域以前都涉及视觉对象识别。令人惊讶的是，在想象和感知过程中，负面情绪并没有以相同的方式调节任何区域的激活。
CEREBRAL blood flow was recorded (using positron emission tomography) while middle-aged subjects viewed or visualized pictures of neutral or aversive stimuli, and then determined whether auditorily presented statements correctly described the stimuli. Visualizing aversive stimuli enhanced cerebral blood flow, relative to visualizing neutral stimuli, in areas 17 (right) and 18 (bilateral), as well as the anterior insula (bilateral) and middle frontal cortex (left). Areas 17 and 18 have been identified as supporting the representations that underlie the experience of imagery, and the anterior insula is a major cortical recipient of input from the autonomic nervous system. Perceiving aversive stimuli enhanced cerebral blood flow, relative to neutral stimuli, in area 46, the angular gyrus and area 19, area 47, and the middle temporal gyrus (all in the left hemisphere). All of these areas have previously been implicated in visual object identification. It is striking that negative emotion did not modulate activation in any areas in the same way during imagery and perception.