A one-pot aqueous synthesis of high-luminescent thiol-capped CdTe and its bioapplication.

A one-pot aqueous synthesis of high-luminescent thiol-capped CdTe and its bioapplication.
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DOI:
10.1166/jnn.2010.2431
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发表时间:
2010-08
影响因子:
--
通讯作者:
Ling Wang;H. Gong;Ruijuan Lv;Yongzhong Wu;Tian-lin Wang
Ling Wang;H. Gong;Ruijuan Lv;Yongzhong Wu;Tian-lin Wang
中科院分区:
工程技术4区
文献类型:
--
作者:
Ling Wang;H. Gong;Ruijuan Lv;Yongzhong Wu;Tian-lin Wang

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我们的研究描述了在水相中采用简便方法合成硫醇封端的高发光(量子产率高达 80%)CdTe 量子点 (QD)。所制备的 CdTe QD 的荧光可以从 500 nm 调整到 650 nm。更重要的是,在β-肌动蛋白缀合后,CdTe QD 成功与活细胞缀合以观察其构型,证明了它们作为生物标记的潜在广泛应用。通过X射线衍射(XRD)、高分辨率透射电子显微镜(HRTEM)和荧光分光光度计研究了产物的晶体结构、形貌和光学性质。
Our study described a synthesis of thiol-capped high-luminescent (quantum yield as high as 80%) CdTe quantum dots (QDs) with a facile method in aqueous phase. The fluorescence of the as-prepared CdTe QDs could be tuned from 500 nm to 650 nm. More importantly, after beta-actin conjugation, the CdTe QDs were successfully conjugated with live cells to observe their configurations, demonstrating their potentially broad application as biolabels. The crystal structure, morphology and optical property of the products were investigated by X-ray diffraction (XRD), high resolution transmission electron microscopy (HRTEM) and fluorescence spectrophotometer.