Organ of Corti kinematics
Organ of Corti kinematics
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DOI：
10.1007/s10162-002-3049-z
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发表时间：
2003-09-01
影响因子：
2.4
通讯作者：
Dallos, P
中科院分区：
文献类型：
--
作者：
Dallos, P
用一个简单的运动学模型考察了Corti器官的内部工作及其与基底膜运动的关系。结果表明，由于杠杆系统体现在Corti器官中，基底膜和纤毛位移之间存在显着的变压器增益。虽然这种转换是非线性的，但在纤毛传感器的狭窄生理相关工作范围内，线性响应普遍存在。该模型还模拟了以外毛细胞长度变化为机械刺激时纤毛的偏转。
The internal workings of the organ of Corti and their relation to basilar membrane motion are examined with the aid of a simple kinematic model. It is shown that, due to the lever system embodied in the organ of Corti, there is a significant transformer gain between basilar membrane and cilia displacements. While this transformation is nonlinear, linear response prevails in the narrow physiologically relevant operating range of the ciliary transducer. The model also simulates cilia deflection when the mechanical stimulus is the length change of outer hair cells.