Fear of cancer recurrence in colorectal cancer survivors.
Fear of cancer recurrence in colorectal cancer survivors.
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DOI：
10.1007/s00520-015-2808-4
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发表时间：
2016-02
期刊：
影响因子：
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通讯作者：
Prins JB
中科院分区：
文献类型：
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作者：
Custers JAE;Gielissen MFM;Janssen SHV;de Wilt JHW;Prins JB
尽管结直肠癌（CRC）长期幸存者普遍报告生活质量良好，但对癌症复发（FCR）的恐惧仍然是一个重要问题。本研究调查了癌症忧虑量表 (CWS) 是否可以检测 CRC 幸存者的高 FCR、FCR 的患病率和特征。 2003 年至 2010 年期间在荷兰拉德堡德大学医学中心成功接受结直肠癌手术的 211 名患者被邀请参加。所有患者均收到一封信息函和调查问卷，用于收集有关人口统计和医疗变量、FCR、痛苦和生活质量的信息。 76 名患者（36%；中位年龄 67.7 岁，范围 41-88 岁）在手术后中位 5.1 年完成了调查问卷。 CWS 的截止分数为 14 或更高是检测高 FCR 的最佳选择。 29 名患者 (38%) 经历了高水平的 FCR，其特点是更高水平的痛苦、创伤后应激症状和较低的生活质量。这些人对疾病相关的诱因反应特别强烈，感到无助、担心，并且日常功能受到限制。高 FCR 与人口或医学变量无关。结直肠癌手术成功后很长一段时间，FCR 是一个严重的问题，损害了相当一部分患者的生活质量。通过 CWS，可以检测高 FCR，从而帮助幸存者接受适当的护理。
Although long-term colorectal cancer (CRC) survivors generally report a good quality of life, fear of cancer recurrence (FCR) remains an important issue. This study investigated whether the Cancer Worry Scale (CWS) can detect high FCR, the prevalence, and characteristics of FCR in CRC survivors. Two hundred and eleven patients who had undergone successful CRC surgery in the period 2003–2010 in the Radboud University Medical Center in the Netherlands were asked to participate. All patients were sent an information letter plus questionnaires for collecting information on demographic and medical variables, FCR, distress, and quality of life. Seventy-six patients (36 %; median age of 67.7 years range 41–88 years) completed the questionnaires a median of 5.1 years after surgery. A cut-off score of 14 or higher on the CWS was optimal to detect high FCR. Twenty-nine patients (38 %) experienced high levels of FCR, characterized by higher levels of distress, post-traumatic stress symptoms, and lower quality of life. These individuals particularly reacted to disease-related triggers, felt helpless, were worried, and experienced limitations in daily functioning. High FCR was not associated with demographic or medical variables. Long after successful CRC surgery, FCR is a serious problem that impairs the quality of life for a substantial proportion of patients. With the CWS, it is possible to detect high FCR and thereby assist survivors in receiving appropriate care.