Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis
Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis
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DOI：
10.1016/s0140-6736(04)17663-0
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发表时间：
2005-01-01
期刊：
影响因子：
168.9
通讯作者：
Ludwig, DS
中科院分区：
文献类型：
--
作者：
Pereira, MA;Kartashov, AI;Ludwig, DS
在过去的三十年里，快餐消费在美国大大增加。然而，快餐对肥胖和2型糖尿病风险的影响却很少受到关注。我们的目的是调查15年来美国报告的快餐习惯与体重和胰岛素抵抗变化之间的关系。方法CARDIA研究的参与者包括3031名年轻（1985-86年18-30岁）的黑人和白人成年人，他们进行了反复的饮食评估。我们使用多元线性回归模型来调查基线和随访时快餐店光顾频率（快餐频率）与15年体重变化和胰岛素抵抗的稳态模型（HOMA）之间的关系。研究发现，白人女性吃快餐的频率最低（每周约1.3次），而其他种族性别群体则最低（每周约两次）。在调整生活方式因素后，基线快餐频率与黑人（p=0.0050）和白人（p=0.0013）的体重变化直接相关。在过去的15年里，快餐频率的变化与白人体重的变化直接相关
Background Fast-food consumption has increased greatly in the USA during the past three decades. However, the effect of fast food on risk of obesity and type 2 diabetes has received little attention. We aimed to investigate the association between reported fast-food habits and changes in bodyweight and insulin resistance over a 15-year period in the USA.Methods Participants for the CARDIA study included 3031 young (age 18-30 years in 1985-86) black and white adults who were followed up with repeated dietary assessment. We used multiple linear regression models to investigate the association of frequency of fast-food restaurant visits (fast-food frequency) at baseline and follow-up with 15-year changes in bodyweight and the homoeostasis model (HOMA) for insulin resistance.Findings Fast-food frequency was lowest for white women (about 1.3 times per week) compared with the other ethnic-sex groups (about twice a week). After adjustment for lifestyle factors, baseline fast-food frequency was directly associated with changes in bodyweight in both black (p=0.0050) and white people (p=0.0013). Change in fast-food frequency over 15 years was directly associated with changes in bodyweight in white individuals (p