PREFERENTIAL EXPRESSION OF CATFISH LIGHT CHAIN IMMUNOGLOBULIN ISOTYPES IN ANTI‐DINITROPHENYL ANTIBODIES
PREFERENTIAL EXPRESSION OF CATFISH LIGHT CHAIN IMMUNOGLOBULIN ISOTYPES IN ANTI‐DINITROPHENYL ANTIBODIES
复制标题
抗二硝基苯基抗体中鲶鱼轻链免疫球蛋白同种型的优先表达
DOI:
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发表时间:
1986
期刊:
影响因子:
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通讯作者:
C. J. Lobb
中科院分区:
文献类型:
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作者:
C. J. Lobb
Previous studies indicated that immunoglobulins of the channel catfish, Ictalurus punctatus, contained two distinct isotypes of light chains. These different light chains, designated F and G, are reminiscent of κ and λ light chains of higher animals. This study was undertaken to establish whether or not there was preferential expression of one of the light chains in antibodies induced to the dinitrophenyl moiety during the course of the catfish humoral antibody response. The results indicated that, although antibody produced very early (1‐2 weeks) after primary immunization contained significant amounts (∼20%) of G light chains, the vast majority (∼90%) of antibody produced later (3 weeks through 1 year) was of the F isotype. Thus fish, as well as higher vertebrates, can express different isotypes of antibody during the immune response.
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DOI:
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发表时间:
1982
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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作者:
Scott,MG;Fleischman,JB
通讯作者:
Fleischman,JB
DOI:
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发表时间:
1984
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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作者:
Basta,P;Briles,DE
通讯作者:
Briles,DE
DOI:
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发表时间:
1983
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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作者:
Fulton,RJ;Nahm,MH;Davie,JM
通讯作者:
Davie,JM
DOI:
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发表时间:
1984
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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作者:
Stall,AM;Loken,MR
通讯作者:
Loken,MR