The Relationship of Cognitive Performance and the Theta-Alpha Power Ratio Is Age-Dependent: An EEG Study of Short Term Memory and Reasoning during Task and Resting-State in Healthy Young and Old Adults.
The Relationship of Cognitive Performance and the Theta-Alpha Power Ratio Is Age-Dependent: An EEG Study of Short Term Memory and Reasoning during Task and Resting-State in Healthy Young and Old Adults.
复制标题
认知表现与Theta-Alpha功率比的关系具有年龄依赖性：健康青年和老年人短时记忆和推理的脑电研究
DOI：
10.3389/fnagi.2017.00364
复制
发表时间：
2017
影响因子：
4.8
通讯作者：
Anderson AE
中科院分区：
文献类型：
--
作者：
Trammell JP;MacRae PG;Davis G;Bergstedt D;Anderson AE
Objective: The Theta-Alpha ratio (TAR) is known to differ based upon age and cognitive ability, with pathological electroencephalography (EEG) patterns routinely found within neurodegenerative disorders of older adults. We hypothesized that cognitive ability would predict EEG metrics differently within healthy young and old adults, and that healthy old adults not showing age-expected EEG activity may be more likely to demonstrate cognitive deficits relative to old adults showing these expected changes. Methods: In 216 EEG blocks collected in 16 young and 20 old adults during rest (eyes open, eyes closed) and cognitive tasks (short-term memory [STM]; matrix reasoning [RM; Raven's matrices]), models assessed the contributing roles of cognitive ability, age, and task in predicting the TAR. A general linear mixed-effects regression model was used to model this relationship, including interaction effects to test whether increased cognitive ability predicted TAR differently for young and old adults at rest and during cognitive tasks. Results: The relationship between cognitive ability and the TAR across all blocks showed age-dependency, and cognitive performance at the CZ midline location predicted the TAR measure when accounting for the effect of age (p < 0.05, chi-square test of nested models). Age significantly interacted with STM performance in predicting the TAR (p < 0.05); increases in STM were associated with increased TAR in young adults, but not in old adults. RM showed similar interaction effects with aging and TAR (p < 0.10). Conclusion: EEG correlates of cognitive ability are age-dependent. Adults who did not show age-related EEG changes were more likely to exhibit cognitive deficits than those who showed age-related changes. This suggests that healthy aging should produce moderate changes in Alpha and TAR measures, and the absence of such changes signals impaired cognitive functioning.
登录
查看更多内容
影响因子：
3.7
作者：
Finnigan, Simon;Robertson, Ian H.
通讯作者：
Robertson, Ian H.
影响因子：
4.8
作者：
Moretti DV
通讯作者：
Moretti DV
影响因子：
3
作者：
Klimesch, W
通讯作者：
Klimesch, W
α 峰值频率的个体间和个体内变异性。
影响因子：
5.7
作者：
Haegens S;Cousijn H;Wallis G;Harrison PJ;Nobre AC
通讯作者：
Nobre AC
影响因子：
3
作者：
Clark, CR;Veltmeyer, MD;Gordon, E
通讯作者：
Gordon, E