Development and application of a Chinese Version of the Language Screening Test (CLAST) in post-stroke patients
Development and application of a Chinese Version of the Language Screening Test (CLAST) in post-stroke patients
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中文版语言筛查测试（CLAST）的开发及在中风后患者中的应用
DOI：
10.1097/md.0000000000022165
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发表时间：
2020-09
期刊：
影响因子：
1.6
通讯作者：
Pan Xiaodong
中科院分区：
文献类型：
--
作者：
Sun Mingyao;Zhan Zhouwei;Chen Bijuan;Xin Jiawei;Chen Xiaochun;Yu Erhan;Lin Lizhen;He Raoli;Pan Xiaodong
摘要 失语症在脑卒中患者中发病率较高，严重损害语言理解、言语交流和社交活动。因此，在脑卒中急性期筛查失语症患者对于语言恢复和康复至关重要。本研究开发了中文版的语言筛查测试（CLAST），并在中风后患者中进行了验证。 CLAST 改编自 Constance 等人开发的语言筛选测试，融入了中国文化和语言特性，并针对 207 名急性中风患者和 89 名稳定失语或非失语患者进行了测试。基于西方失语症电池（WAB）测试，评估其信度和效度。通过 ROC 曲线分析确定中国患者 CLAST 的临界值。 CLAST由5个分项测试和15个项目组成，其中包括2个分项，即表达（8分，评估命名、重复和自动语音）和接受（最多7分，评估图片识别和口头指令）指标。问卷的替代形式信度分析显示，重测相关系数为0.945（P < .001）。三个评级团队的组内相关系数>0.98（P < .001）。内部一致性分析显示 Cronbach's alpha 系数为 0.909 (P < .001)。非失语组得分高于失语组（14.2±1.3 vs 10.6±3.8）（P< .01）。通过因子分析，问卷显示出良好的结构效度。 ROC 曲线分析显示 CLAST 具有较高的敏感性和特异性，截止值为 13.5。 CLAST适用于中国脑卒中后急性期患者，具有较高的信度、效度、敏感性和特异性。
Abstract Aphasia shows high incidence in stroke patients and seriously impairs language comprehension, verbal communication, and social activities. Therefore, screening aphasic patients during the acute phase of stroke is crucial for language recovery and rehabilitation. The present study developed a Chinese version of the Language Screening Test (CLAST) and validated it in post-stroke patients. The CLAST was adapted from the Language Screening Test developed by Constance et al to incorporate Chinese cultural and linguistic specificities, and administered to 207 acute stroke patients and 89 stabilized aphasic or non-aphasic patients. Based on the Western Aphasia Battery (WAB) test, its reliability and validity were assessed. A cut-off for the CLAST in Chinese patients was determined by ROC curve analysis. The CLAST comprised 5 subtests and 15 items, including 2 subscores, namely expression (8 points, assessing naming, repetition, and automatic speech) and receptive (7 points maximum, evaluating picture recognition, and verbal instructions) indexes. Analysis of the alternate-form reliability of the questionnaire showed a retest correlation coefficient of 0.945 (P < .001). Intraclass correlation coefficients of three rating teams were >0.98 (P < .001). Internal consistency analysis showed a Cronbach's alpha coefficient of 0.909 (P < .001). The non-aphasia group showed higher scores than the aphasia group (14.2 ± 1.3 vs 10.6 ± 3.8) (P < .01). The questionnaire showed good construct validity by factor analysis. ROC curve analysis showed high sensitivity and specificity for the CLAST, with a cut-off of 13.5. The CLAST is suitable for Chinese post-stroke patients during the acute phase, with high reliability, validity, sensitivity, and specificity.
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影响因子：
6.1
作者：
Wu JB;Lyu ZH;Liu XJ;Li HP;Wang Q
通讯作者：
Wang Q
影响因子：
2.7
作者：
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通讯作者：
Tijana Simic;E. Rochon;Elissa Greco;R. Martino
影响因子：
4.4
作者：
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通讯作者：
Charles Ellis;Rose Y. Hardy;R. Lindrooth
影响因子：
1.2
作者：
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通讯作者：
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影响因子：
3.5
作者：
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通讯作者：
Kahan, Thomas