Sex Differences in the Association Between Internalizing Symptoms and Craving in Methamphetamine Users
Sex Differences in the Association Between Internalizing Symptoms and Craving in Methamphetamine Users
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DOI：
10.1097/adm.0000000000000250
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发表时间：
2016-11-01
影响因子：
5.5
通讯作者：
Ray, Lara A.
中科院分区：
文献类型：
--
作者：
Hartwell, Emily E.;Moallem, Nathasha R.;Ray, Lara A.
目的：甲基苯丙胺（MA）使用者经常有大量的精神共病，近三分之一的人报告终身情绪障碍，超过四分之一的人报告终身焦虑障碍。与男性相比，女性MA用户更有可能认可抑郁和焦虑症状。渴望与MA使用者的情绪/焦虑症状有关。为了扩大文学的性别差异在MA使用disorder，本研究探讨性别的作用作为一个调解人之间的关系情绪/焦虑症状和MA craving.Methods：参与者（N=203）是nontreatment-seeking，目前MA用户，从洛杉矶社区招募在一个更大的药物治疗试验。在评估访问时，参与者完成了多项测量，包括甲基苯丙胺冲动问卷，贝克抑郁量表和贝克焦虑量表。结果：抑郁症与MA渴求之间的关系受性别的调节（F=6.18，P=0.01），男性的关系是积极的和显著的（P
Objectives:Methamphetamine (MA) users often have substantial psychiatric comorbidities, with nearly a third reporting lifetime mood disorders and over a quarter reporting lifetime anxiety disorders. Female MA users are more likely to endorse depression and anxiety symptoms compared with men. Craving has been related to mood/anxiety symptoms in MA users. To extend the literature on sex differences in MA use disorder, the present study examines the role of sex as a moderator of the relationship between mood/anxiety symptoms and MA craving.Methods:Participants (N=203) were nontreatment-seeking, current MA users, recruited from the Los Angeles community for enrollment in a larger pharmacotherapy trial. At the assessment visit, participants completed multiple measures including the Methamphetamine Urge Questionnaire, the Beck Depression Inventory, and the Beck Anxiety Inventory.Results:The relationship between depression symptomatology and MA craving was moderated by sex (F=6.18, P=0.01), such that the relationship was positive and significant for men (P