Widow Inheritance and HIV Prevalence in Bondo District, Kenya: Baseline Results from a Prospective Cohort Study
Widow Inheritance and HIV Prevalence in Bondo District, Kenya: Baseline Results from a Prospective Cohort Study
复制标题
DOI：
10.1371/journal.pone.0014028
复制
发表时间：
2010-11-17
期刊：
影响因子：
3.7
通讯作者：
Weiss, Noel S.
中科院分区：
文献类型：
--
作者：
Agot, Kawango E.;Stoep, Ann Vander;Weiss, Noel S.
背景资料：寡妇继承是撒哈拉以南非洲的一种普遍文化习俗，被认为会增加艾滋病毒传播的风险。我们提出了一项研究的基线结果，旨在调查寡妇继承和HIV acquisition.Methods和结果之间的关联：我们进行了一个前瞻性队列研究的基线数据的横断面分析，调查如果寡妇继承是一个风险的做法，艾滋病毒感染。研究参与者是1，987名寡妇，他们接受了关于其继承状况和性行为概况的采访，并进行了艾滋病毒检测。在这些寡妇中，56.3%是继承的。非继承寡妇和继承寡妇的艾滋病毒感染率相似，为63%。我们分层暴露状态的寡妇的继承人和继承的原因的关系，并重新检查了艾滋病毒感染状况的四个亚组的继承妇女相对于非继承妇女的艾滋病毒感染状况。当调整年龄和正规教育水平时，由非亲属继承性仪式的寡妇比没有继承的寡妇感染的可能性要大得多（OR = 2.07; 95%CI 1.49-2.86）;由亲属继承用于性仪式的寡妇也有较高的HIV感染几率（OR = 1.34; 95%CI = 1.07-1.70）。寡妇谁是由亲属继承的陪伴是不太可能比妇女谁没有继承被感染HIV（OR = 0.85; 95%CI 0.63-1.14）。结论：艾滋病毒感染率在继承寡妇的变化取决于他们为什么和谁继承。队列研究将确定该样本中艾滋病毒血清反应阴性的寡妇感染艾滋病毒的风险。
Background: Widow Inheritance is a widespread cultural practice in sub-Saharan Africa that has been postulated as contributing to risk of HIV transmission. We present baseline results from a study designed to investigate the association between widow inheritance and HIV acquisition.Methods and Findings: We performed a cross-sectional analysis of baseline data from a prospective cohort study to investigate if widow inheritance is a risk practice for HIV infection. Study participants were 1,987 widows who were interviewed regarding their inheritance status and sexual behavior profile and tested for HIV. Of these widows, 56.3% were inherited. HIV prevalence, at 63%, was similar among non-inherited and inherited widows. We stratified exposure status by the relationship of the widow to the inheritor and the reason for inheritance, and reexamined the HIV status of four subgroups of inherited women relative to the HIV status of non-inherited women. When adjusting for age and level of formal education, widows who were inherited by non-relatives for sexual ritual were significantly more likely to be infected than widows who were not inherited (OR = 2.07; 95% CI 1.49-2.86); widows who were inherited by relatives for sexual ritual also had elevated odds of HIV infection (OR = 1.34; 95% CI = 1.07-1.70). Widows who were inherited by relatives for companionship were less likely than women who were not inherited to be infected with HIV (OR = 0.85; 95% CI 0.63-1.14).Conclusions: HIV prevalence among inherited widows varied depending upon why and by whom they were inherited. The cohort study will determine the risk for HIV acquisition among the HIV seronegative widows in this sample.