Burst-firing sharpens frequency-tuning in primary auditory cortex
Burst-firing sharpens frequency-tuning in primary auditory cortex
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DOI：
10.1097/00001756-199602290-00018
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发表时间：
1996-02-29
期刊：
影响因子：
1.7
通讯作者：
Smith, GM
中科院分区：
文献类型：
--
作者：
Eggermont, JJ;Smith, GM
本文研究了氯胺酮麻醉猫初级听觉皮层中46个高放电单元的频率调谐。爆炸发射的调谐曲线明显比整体发射速率条件下的调谐曲线窄，因此，比孤立尖峰条件下的调谐曲线窄得多。发现爆炸发射超出了从调制泊松过程预测的结果，因此不能根据发射速率标准的变化来解释结果。我们提出，听觉皮层的突发放电可能选择性地增强由动物的行为状态及其刺激历史动态控制的频率调谐。因此，突发放电可能对皮质处理具有功能意义。
FREQUENCY-TUNING in 46 high-firing single units from primary auditory cortex of ketamine-anaesthetized cats was studied separately for isolated-spike firing and burst spike firing. The tuning curve for burst firing was significantly narrower than for the overall firing rate condition and, consequently, much narrower than for the isolated spikes. The burst firing was found in excess of that predicted from a modulated Poisson process, so the results cannot be explained on basis of a change in firing rate criterion. We propose that burst firing in auditory cortex may selectively enhance frequency tuning dynamically controlled by the behavioural state of the animal as well as its stimulus history. Thus burst firing may have functional implications for cortical processing.