ACTIVE: A cognitive intervention trial to promote independence in older adults
ACTIVE: A cognitive intervention trial to promote independence in older adults
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DOI：
10.1016/s0197-2456(01)00139-8
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发表时间：
2001-08-01
期刊：
影响因子：
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通讯作者：
Kleinman, K
中科院分区：
文献类型：
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作者：
Jobe, JB;Smith, DM;Kleinman, K
独立和有活力老年人的高级认知训练(ACTIVE)试验是一项随机、对照、单掩蔽试验，旨在确定认知训练干预(记忆、推理和信息处理速度)是否会影响基于认知的日常功能测量，这些干预措施此前已被发现在实验室或小规模现场条件下成功地改善了智力。1998年开始招生，为期两年的后续行动将于2002年1月完成。主要结果侧重于衡量认知需求的日常功能，包括财务管理、食物准备、用药和驾驶。次要结果包括与健康相关的生活质量、流动性和卫生服务利用率。试验参与者(n=2832)年龄在65岁及以上，在进入试验时，没有明显的认知、身体或功能下降。由于其规模和精心开发的严谨性，Active可能会成为未来此类性质的行为医学试验的指南。爱思唯尔科学公司出版，2001年。
The Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial is a randomized, controlled, single-masked trial designed to determine whether cognitive training interventions (memory, reasoning, and speed of information processing), which have previously been found to be successful at improving mental abilities under laboratory or small-scale field conditions, can affect cognitively based measures of daily functioning. Enrollment began during 1998; 2-year follow-up will be completed by January 2002. Primary outcomes focus on measures of cognitively demanding everyday functioning, including financial management, food preparation, medication use, and driving. Secondary outcomes include health-related quality of life, mobility, and health-service utilization. Trial participants (n = 2832) are aged 65 and over, and at entry into the trial, did not have significant cognitive, physical, or functional decline. Because of its size and the carefully developed rigor, ACTIVE may serve as a guide for future behavioral medicine trials of this nature. Published by Elsevier Science Inc. 2001.