SpEED: fast computation of sensitive spaced seeds
SpEED: fast computation of sensitive spaced seeds
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DOI：
10.1093/bioinformatics/btr368
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发表时间：
2011-09-01
期刊：
影响因子：
5.8
通讯作者：
Bigvand, Anahita Mansouri
中科院分区：
文献类型：
--
作者：
Ilie, Lucian;Ilie, Silvana;Bigvand, Anahita Mansouri
多个间隔种子代表了生物信息学中相似性搜索的最新技术，在序列比对、阅读图谱、寡核苷酸设计等领域都有应用。我们介绍了一个计算高度敏感的多个间隔种子的软件程序SPEED。与现有的领先软件程序相比，速度可以快几个数量级，计算出更好的种子。
Multiple spaced seeds represent the current state-of-the-art for similarity search in bioinformatics, with applications in various areas such as sequence alignment, read mapping, oligonucleotide design, etc. We present SpEED, a software program that computes highly sensitive multiple spaced seeds. SpEED can be several orders of magnitude faster and computes better seeds than the existing leading software programs.