IMPACT OF MATERNAL SEAFOOD DIET ON FETAL EXPOSURE TO MERCURY, SELENIUM, AND LEAD

IMPACT OF MATERNAL SEAFOOD DIET ON FETAL EXPOSURE TO MERCURY, SELENIUM, AND LEAD
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DOI:
10.1080/00039896.1992.9938348
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发表时间:
1992-05-01
期刊:
ARCHIVES OF ENVIRONMENTAL HEALTH
影响因子:
--
通讯作者:
VIDERO, T
VIDERO, T
中科院分区:
其他
文献类型:
--
作者:
GRANDJEAN, P;WEIHE, P;VIDERO, T

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法罗群岛1,023名新生儿的脐带血显示,血汞浓度中位数为121 nmol/l(24.2 μ g/l);其中250份样本(25.1%)的血汞浓度超过200 nmol/l(40 μ g/l)。母亲头发汞浓度的中位数为22.5纳摩尔/克(4.5微克/克),130个样本(12.7%)的浓度超过50纳摩尔/克(10微克/克)。怀孕期间经常摄入鲸鱼肉晚餐,在较小的程度上,经常食用鱼,增加胎次或年龄与脐带血和头发中的高汞浓度有关。如果母亲偶尔摄入酒精饮料,血汞水平略低。血汞与血硒中度相关(中位数为1.40 μ mol/l)。硒浓度的增加与鲸鱼肉的摄入、戒酒、足月分娩和高产次有关。脐带血中的铅含量较低(中位数为82 nmol/l),特别是如果母亲晚餐经常吃鱼并且戒烟的话。
Umbilical cord blood from 1 023 consecutive births in the Faroe Islands showed a median blood-mercury concentration of 121 nmol/l (24.2-mu-g/l); 250 of those samples (25.1%) had blood-mercury concentrations that exceeded 200 nmol/l (40-mu-g/l). Maternal hair mercury concentrations showed a median of 22.5 nmol/g (4.5-mu-g/g), and 130 samples (12.7%) contained concentrations that exceeded 50 nmol/g (10-mu-g/g). Frequent ingestion of whale meat dinners during pregnancy and, to a much lesser degree, frequent consumption of fish, and increased parity or age were associated with high mercury concentrations in cord blood and hair. Blood-mercury levels were slightly lower if the mother had occasionally ingested alcoholic beverages. Mercury in blood correlated moderately with blood selenium (median, 1.40-mu-mol/l). Increased selenium concentrations were associated with intake of whale meat, alcohol abstention, delivery after term, and high parity. Lead in cord blood was low (median, 82 nmol/l), particularly if the mothers had frequently had fish for dinner and had abstained from smoking.