Cytomegalovirus infections in homosexual men. An epidemiological study.
Cytomegalovirus infections in homosexual men. An epidemiological study.
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DOI：
10.7326/0003-4819-99-3-326
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发表时间：
1983-09
影响因子：
39.2
通讯作者：
Lawrence Mintz;Drew Wl;Richard C. Miner;Erwin H. Braff
中科院分区：
文献类型：
--
作者：
Lawrence Mintz;Drew Wl;Richard C. Miner;Erwin H. Braff
本文对237名男同性恋者进行了平均14.1个月的巨细胞病毒抗体（IgG和IgM）检测和尿病毒培养。巨细胞病毒IgG抗体初筛阳性率为86.9%。在随访的第9个月，71%的血清敏感男性已经感染了巨细胞病毒。在研究期间，32%的血清阳性男性出现巨细胞病毒尿。巨细胞病毒IgM抗体间歇性地存在于95%的IgG血清阳性男性的血清中，这表明潜伏感染或再次暴露于外源性病毒的频繁再激活已经发生。在调查的七种性行为中，只有被动肛门-生殖器性交与巨细胞病毒感染相关（p = 0.008）。
Levels of cytomegalovirus antibody (IgG and IgM) were measured and urine viral cultures were done in 237 homosexual men over a mean period of 14.1 months. The initial prevalence of cytomegalovirus IgG antibody was 86.9%. By the 9th month of follow-up, 71% of serosusceptible men had become infected with cytomegalovirus. During the study period cytomegaloviruria was noted in 32% of seropositive men. Cytomegalovirus IgM antibody was intermittently present in the serum of 95% of IgG-seropositive men, suggesting that frequent reactivation of latent infection or reexposure to exogenous virus had occurred. Of seven sexual practices investigated, only passive anal-genital intercourse correlated with the acquisition of cytomegalovirus infection (p = 0.008).