The effect of anterior cruciate ligament reconstruction on the progression of osteoarthritis.
The effect of anterior cruciate ligament reconstruction on the progression of osteoarthritis.
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DOI：
10.2174/1874325001206010506
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Getgood A
中科院分区：
文献类型：
--
作者：
Norris R;Thompson P;Getgood A
前交叉韧带断裂（ACL）是一种常见的损伤，特别是在年轻的运动成年人中。早发性骨关节炎（OA）可能是这种损伤的破坏性和难以管理的后果。重建ACL的技术一直在进步，但这对OA进展的影响尚不清楚。许多因素影响ACL损伤后OA的发展，包括关节软骨的直接和间接创伤、相关关节损伤、慢性胫股关节不稳定和多种酶途径。本综述将总结围绕这些领域的现有证据，并描述一些可能对未来这些损伤的管理产生影响的最新进展。
Anterior cruciate ligament rupture (ACL) is a common injury, particularly among young sporting adults. Early onset osteoarthritis (OA) can be a devastating and difficult to manage consequence of such an injury. The techniques for reconstructing the ACL are advancing all the time, but the effect that this has on the progression of OA is less well understood. Many factors affect the development of OA following an ACL injury, including direct and indirect trauma to the articular cartilage, associated meniscal injuries, chronic tibiofemoral joint instability, and multiple enzymatic pathways. This review will summarize the current evidence surrounding each of these areas, and describe some of the recent developments that may have an impact on the management of these injuries in the future.