Patients with spinal cord cavernous malformations are at an increased risk for multiple neuraxis cavernous malformations.
Patients with spinal cord cavernous malformations are at an increased risk for multiple neuraxis cavernous malformations.
复制标题
脊髓海绵状血管瘤患者发生多发性神经轴海绵状血管瘤的风险增加。
DOI：
10.1097/00006123-199907000-00008
复制
发表时间：
1999
期刊：
影响因子：
4.8
通讯作者：
R. Spetzler
中科院分区：
文献类型：
--
作者：
A. Vishteh;J. Zabramski;R. Spetzler
目的
确定最初表现为脊髓髓内（IMSC）海绵状畸形而不了解神经轴其他部位海绵状畸形的患者中多发性神经轴海绵状畸形的患病率。
方法
分析了17例患者的医院记录和影像学文件，这些患者随后接受了IMSC海绵状血管畸形（组织学证实）的手术切除，并接受了脑磁共振成像研究。这17例患者代表了在同一时期接受IMSC海绵状血管畸形手术切除的32例患者的子集。
结果
17例患者中，8例（47%）患有多发性海绵状血管畸形。该组由5名女性和3名男性组成（平均年龄35.9岁）。有4名白人和4名西班牙裔患者。
结论
在患有IMSC海绵状畸形的患者中，神经轴多发性海绵状畸形的患病率似乎增加。这一发现对这些患者的评估和管理具有重要意义，在某些情况下，对他们的家庭成员也有重要意义。
OBJECTIVE
To determine the prevalence of multiple neuraxis cavernous malformations in patients who initially presented with intramedullary spinal cord (IMSC) cavernous malformations without knowledge of cavernous malformations elsewhere in the neuraxis.
METHODS
Hospital records and radiographic files were analyzed for 17 patients who subsequently underwent surgical resection of an IMSC cavernous malformation (histologically proven) and also underwent brain magnetic resonance imaging studies. These 17 patients represented a subset of 32 patients who underwent surgical resection of an IMSC cavernous malformation during the same period.
RESULTS
Of 17 patients, 8 (47%) harbored multiple cavernous malformations. This group was composed of five women and three men (mean age, 35.9 yr). There were four Caucasian and four Hispanic patients.
CONCLUSION
The prevalence of multiple cavernous malformations in the neuraxis seems to be increased in patients who harbor IMSC cavernous malformations. This finding has important implications for the evaluation and management of these patients and, in some cases, their family members.