Linear DNA of Borrelia species and antigenic variation.

Linear DNA of Borrelia species and antigenic variation.
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DOI:
10.1016/0966-842x(93)90139-i
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发表时间:
1993-09-01
影响因子:
15.9
通讯作者:
Barbour, A G
Barbour, A G
中科院分区:
生物学1区
文献类型:
--
作者:
Barbour, A G

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Members of the genus Borrelia may be unique among prokaryotic organisms in having a polyploid genome that is mostly linear. The smaller linear duplex replicons in these organisms have been called plasmids, but there is justification for designating them minichromosomes instead. The antigenic identities of the agents of Lyme disease and relapsing fever are largely determined by these extrachromosomal genes.