Antioxidative activity of synthetic melanins. Cardiolipin liposome model.
Antioxidative activity of synthetic melanins. Cardiolipin liposome model.
复制标题
合成黑色素的抗氧化活性。
DOI：
10.1016/0304-4165(92)90121-a
复制
发表时间：
1992
期刊：
影响因子：
--
通讯作者：
T. Wilczok
中科院分区：
文献类型：
--
作者：
M. Porebska;N. Sakina;K. Stępień;A. Dontsov;T. Wilczok
The inhibiting effect of melanin synthesized from dihydroxyphenylalanine (DOPA), dopamine, adrenaline and adrenolutin on the ultraviolet-or the Fe 2+-ascorbic acid-induced lipid peroxidation. Antioxidative activity of melanins enhances in the order: dopamine-melanin< melanin synthesized from dopamine in the presence of Cu 2+< DOPA-melanin< melanin synthetized from adrenaline in the presence of Cu 2+⋟ adrenolutin-melanin, and correlates with thei ability to scavenge superoxide anion radical. The optical screening effect of the investigated melanins in the inhibition of lipid peroxidation was not higher than 15% for the most active melanins.
