Morbidity among farm workers in a desert country in relation to long-term exposure to pesticides

Morbidity among farm workers in a desert country in relation to long-term exposure to pesticides
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DOI:
10.5271/sjweh.301
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发表时间:
1998-06-01
影响因子:
6.3
通讯作者:
Basha, M
Basha, M
中科院分区:
医学2区
文献类型:
--
作者:
Gomes, J;Lloyd, O;Basha, M

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目标 长期接触低浓度农药的农场工人很少表现出具有临床意义的体征和症状。本研究调查亚临床。方法将农民工农场工人(N=226)与参照者(N=226)以及刚刚进入该国农场工作的新农场工人(N=92)进行比较。测量乙酰胆碱酯酶活性,进行瞄准测试和数字符号测试,并通过问卷收集发病情况。结果 已建立的农场工人的红细胞乙酰胆碱酯酶活性和血红蛋白调节的红细胞乙酰胆碱酯酶活性显着降低。既定农场工人的瞄准和数字符号测试结果也明显较低。在发病情况方面,老农场工人报告的结膜刺激(47.3%)、流泪(52.2%)、视力模糊(63.3%)、头晕(55.2%)、头痛(63.7%)、肌肉疼痛(61.1%)和虚弱(76.6%)的数量在统计学上显着高于参考对象和新农场工人。结论诸如本研究中建议的健康投诉和客观参数,将适合作为确定最容易遭受农药毒性风险的农场工人的标准,以及作为启动控制和减少接触的措施的标准。
Objectives Farm workers chronically exposed to low levels of pesticides seldom show signs and symptoms of clinical significance. This study investigates subclinical. morbidity patterns among male farm workers in a desert country.Methods Migrant-established farm workers (N=226) were compared with referents (N=226) and with new farm workers (N=92) who had just entered the country to work on farms. Acetylcholinesterase activity was measured, the aiming test and digit symbol test were applied, and a morbidity profile was collected with a questionnaire.Results The erythrocyte acetylcholinesterase activity and hemoglobin-adjusted erythrocyte acetylcholinesterase activity were significantly depleted in the established farm workers. The results of the aiming and digit symbol tests were also significantly lower for the established farm workers. For the morbidity profile, irritated conjunctiva (47.3%), watery eyes (52.2%), blurred vision (63.3%), dizziness (55.2%), headache (63.7%), muscular pain (61.1 %), and weakness (76.6%) were reported by established farm workers in statistically significantly higher numbers than by the referents and new farm workers.Conclusions Morbidity patterns, such as the health complaints and objective parameters suggested in this study, would be suitable as criteria for identifying farm workers most at risk from pesticide toxicity and as criteria for initiating measures to control and reduce exposure.