Frame-Guided Assembly of Vesicles with Programmed Geometry and Dimensions
Frame-Guided Assembly of Vesicles with Programmed Geometry and Dimensions
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DOI：
10.1002/anie.201310715
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发表时间：
2014-03-03
影响因子：
16.6
通讯作者：
Liu, Dongsheng
中科院分区：
文献类型：
--
作者：
Dong, Yuanchen;Sun, Yawei;Liu, Dongsheng
在分子自组装中，分子形成有组织的结构或图案。自组装过程的控制是一个重要而具有挑战性的课题。受决定真核细胞形状的细胞膜蛋白脂质双层系统的启发，我们开发了框架引导组装过程作为制备具有编程几何形状和尺寸的异质囊泡的一般策略。这种方法提供了对自组装的更大控制，这可能有助于理解细胞膜的形成机制以及功能。
In molecular self-assembly molecules form organized structures or patterns. The control of the self-assembly process is an important and challenging topic. Inspired by the cytoskeletal-membrane protein lipid bilayer system that determines the shape of eukaryotic cells, we developed a frame-guided assembly process as a general strategy to prepare heterovesicles with programmed geometry and dimensions. This method offers greater control over self-assembly which may benefit the understanding of the formation mechanism as well as the functions of the cell membrane.