Progressive fiber tract affections after temporal lobe surgery
Progressive fiber tract affections after temporal lobe surgery
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DOI：
10.1111/epi.12077
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发表时间：
2013-04-01
期刊：
影响因子：
5.6
通讯作者：
Weber, Bernd
中科院分区：
文献类型：
--
作者：
Faber, Jennifer;Schoene-Bake, Jan-Christoph;Weber, Bernd
一些研究报道了颞叶癫痫（TLE）患者术后短时间内颞叶手术后白质结构的变化。我们在术后36个月和12个月两个时间点对20例左侧TLE患者进行弥散成像，观察术后可塑性。我们观察到纤维束完整性的丧失主要发生在同侧颞叶纤维束。我们的数据显示，手术干预后大脑连通性的重塑持续了更长的时间。这些可塑性变化对功能的影响必须加以探讨。
Several studies reported changes in white matter architecture following temporal lobe surgery in patients with temporal lobe epilepsy (TLE) at short intervals after surgery. We investigated 20 patients with left-sided TLE using diffusion-imaging at two time points, that is, at 36months and 12months after surgery, to investigate postsurgical plasticity. We observed a loss of fiber tract integrity mainly in fiber tracts of the ipsilateral temporal lobe. Our data show that the remodeling of brain connectivity after surgical interventions continues for longer time periods. The functional implications of these plastic changes will have to be explored.