Rh(III)-Catalyzed Selective Coupling of N-Methoxy-1H-indole-1-carboxamides and Aryl Boronic Acids

Rh(III)-Catalyzed Selective Coupling of N-Methoxy-1H-indole-1-carboxamides and Aryl Boronic Acids
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Rh(III) 催化 N-甲氧基-1H-吲哚-1-甲酰胺与芳基硼酸的选择性偶联

DOI:
10.1021/ol5014312
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发表时间:
2014-07-04
期刊:
影响因子:
5.2
通讯作者:
Cui, Sunliang
Cui, Sunliang
中科院分区:
化学1区
文献类型:
--
作者:
Zheng, Jing;Zhang, Yan;Cui, Sunliang

文献摘要

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A Rh(III)-catalyzed selective coupling of N-methoxy-1H-indole-1-carboxamide and aryl boronic acids is reported. The coupling is mild and efficient toward diverse product formation, with selective C-C and C-C/C-N bond formation. Kinetic isotope effects studies were conducted to reveal a mechanism of C H activation and electrophilic addition.