Tone-burst auditory brainstem response wave V latencies in normal-hearing and hearing-impaired ears
Tone-burst auditory brainstem response wave V latencies in normal-hearing and hearing-impaired ears
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DOI：
10.1121/1.4935516
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发表时间：
2015-11-01
影响因子：
2.4
通讯作者：
Gorga, Michael P.
中科院分区：
文献类型：
--
作者：
Lewis, James D.;Kopun, Judy;Gorga, Michael P.
在听觉功能比较中，用于等同听力正常 (NH) 耳朵和听力损失 (HL) 耳朵之间刺激水平 [声压水平 (SPL) 或感觉水平 (SL)] 的指标可能会影响结果的解释。当刺激水平以 dB SL 为单位时，由于灵敏度降低，HL 耳朵会呈现较高的 SPL。因此，可能很难确定 NH 耳朵和 HL 耳朵之间的差异是否是由于耳蜗病理学或耳蜗力学水平相关的变化所致。就耳蜗力学的水平依赖性变化导致听觉脑干反应潜伏期而言，正常耳朵和病理耳朵之间的比较可能取决于进行比较时的刺激水平。为了验证这一假设，我们测量了 16 只 NH 耳朵和 15 只轻度至中度 HL 耳朵的 V 波潜伏期。当 SL 中的刺激水平相等时，HL 耳朵中的潜伏期较短。然而，当 SPL 中的刺激水平相等时，NH 耳朵和 HL 耳朵的延迟相似。这些观察结果表明，相对于 HL 的影响，刺激水平对 V 波潜伏期的影响较大，至少在轻度至中度 HL 的情况下是如此。 (C) 2015 年美国声学学会。
The metric used to equate stimulus level [sound pressure level (SPL) or sensation level (SL)] between ears with normal hearing (NH) and ears with hearing loss (HL) in comparisons of auditory function can influence interpretation of results. When stimulus level is equated in dB SL, higher SPLs are presented to ears with HL due to their reduced sensitivity. As a result, it may be difficult to determine if differences between ears with NH and ears with HL are due to cochlear pathology or level-dependent changes in cochlear mechanics. To the extent that level-dependent changes in cochlear mechanics contribute to auditory brainstem response latencies, comparisons between normal and pathologic ears may depend on the stimulus levels at which comparisons are made. To test this hypothesis, wave V latencies were measured in 16 NH ears and 15 ears with mild-to-moderate HL. When stimulus levels were equated in SL, latencies were shorter in HL ears. However, latencies were similar for NH and HL ears when stimulus levels were equated in SPL. These observations demonstrate that the effect of stimulus level on wave V latency is large relative to the effect of HL, at least in cases of mild-to-moderate HL. (C) 2015 Acoustical Society of America.