Sugar metabolism by Brucellae
Sugar metabolism by Brucellae
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DOI：
10.1016/s0378-1135(02)00212-2
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发表时间：
2002-12-20
影响因子：
3.3
通讯作者：
Paulsen, I
中科院分区：
文献类型：
--
作者：
Essenberg, RC;Seshadri, R;Paulsen, I
布鲁氏菌的代谢能力最初是作为区分它们彼此和与其他属的一种手段而引起兴趣的。研究了一些不寻常的特征，特别是赤藓糖醇的利用，希望它们能阐明致病性。随着现代遗传方法和基因组测序的出现，现在有可能对生物体的总体能力有一个很好的了解，并进行测试来证实这些推断。布鲁氏菌似乎是一种相当正常的α -变形菌门成员，但有一些不同。一些问题仍然存在，比如布鲁氏菌是否使用enterner - doudoroff途径。一些与碳水化合物利用有关的基因已被证明在毒力中起重要作用。(C) 2002 Elsevier Science B.V.版权所有
The metabolic capabilities of the species of Brucella were originally of interest as a means of distinguishing them from each other and from other genera. Certain unusual characteristics, especially erythritol utilization, were studied in the hopes they would shed light on the pathogenicity. With the advent of modern genetic methods and genomic sequencing, it is now possible to get a good idea of the total capabilities of the organism and to do tests to confirm these deductions. Brucella appears to be a fairly normal member of the alpha-proteobacteria, but with some differences. A few questions remain, such as whether Brucella uses the Entner-Doudoroff pathway. Some of the genes in carbohydrate utilization have been shown to be important in virulence. (C) 2002 Elsevier Science B.V. All rights reserved.