Microbial contamination of hydrogel contact lenses
Microbial contamination of hydrogel contact lenses
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DOI：
10.1111/j.1365-2672.1997.tb03598.x
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发表时间：
1997-05-01
影响因子：
4
通讯作者：
Holden, BA
中科院分区：
文献类型：
--
作者：
Gopinathan, U;Stapleton, F;Holden, BA
接触镜（CL）的细菌污染可能导致CL相关的角膜感染和炎症。本研究报告了在日常和长期佩戴期间随时间推移的CL生物群。在澳大利亚和印度人群中评价了58%水、离子型水凝胶CL和38%水、非离子型水凝胶CL的微生物污染。在18个月的时间里，对50名佩戴者进行了反复采样。与每日佩戴CL相比，过夜使用CL不会改变阳性培养物的频率，也不会改变微生物的谱。CL污染的类型和频率在CL类型之间没有差异。与澳大利亚人群相比，从印度人群中回收的阳性培养物更频繁。链球菌属和丙酸杆菌属（Propionibacterium spp.）更频繁地与澳大利亚人口隔离。真菌和芽孢杆菌属他们经常与印第安人隔离。仅正常CL生物群不能解释长期佩戴中感染和炎症率的增加。
Bacterial contamination of contact lenses (CLs) may contribute to CL-related corneal infection and inflammation. This study reports CL biota over time during daily and extended wear. Microbial contamination of a 58% water, ionic hydrogel CL and a 38% water, non-ionic hydrogel CL was evaluated in an Australian and an Indian population. Fifty wearers were repeatedly sampled over 18 months. Overnight CL use did not alter the frequency of positive cultures, nor the spectrum of organisms compared with daily CL wear. There were no differences in type and frequency of CL contamination between the CL types. Positive cultures were more frequently recovered from the Indian population compared with the Australian population. Streptococcus spp. and Propionibacterium spp. were more frequently isolated from the Australian population. Fungi and Bacillus spp. were more frequently isolated from the Indian population. Normal CL biota alone cannot explain the increased rate of infection and inflammation in extended wear.