Evaluation of the antifungal and plasma membrane H+-ATPase inhibitory action of ebselen and two ebselen analogs in S-cerevisiae cultures
Evaluation of the antifungal and plasma membrane H+-ATPase inhibitory action of ebselen and two ebselen analogs in S-cerevisiae cultures
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DOI：
10.3109/14756360903179419
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发表时间：
2010-06-01
影响因子：
5.6
通讯作者：
Lau-Cam, Cesar
中科院分区：
文献类型：
--
作者：
Billack, Blase;Pietka-Ottlik, Magdalena;Lau-Cam, Cesar
质膜h2。然而，在抑制Pma1p作用方面，效价按1 > 3 > 2的顺序递减。这些活性的大小似乎与相应的log P值相关，化合物2是三种化合物中最亲水和活性最低的。
The plasma membrane H 2. However, in terms of inhibitory action on Pma1p, the potency decreased in the order 1 > 3 > 2. The magnitude of these activities appears to be correlated with the corresponding log P values, with compound 2 being the most hydrophilic and the least active of the three.